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Simcell Osmosis with a Water-Permeable Membrane

In a simcell with a water permeable membrane, the inside contains 0.30 M sucrose and the outside contains 0.10 M sucrose; assuming sucrose cannot cross the membrane, what is the direction of net water movement and which side is hypertonic?

Subject: Biology Chapter: Cell Size and Transport Topic: Osmolarity and Tonicity Answer included
a simcell with a water permeable membrane osmosis semipermeable membrane tonicity osmolarity hypotonic hypertonic isotonic
Accepted answer Answer included

Problem

A simcell with a water permeable membrane separates two compartments:

  • Inside (simcell): 0.30 M sucrose
  • Outside solution: 0.10 M sucrose

The membrane is permeable to water but not to sucrose. Determine (1) the direction of net water movement and (2) which side is hypertonic relative to the other.

Key biological idea

With a semipermeable (water-permeable) membrane, net osmosis moves water from the side with lower effective solute concentration (lower osmolarity; hypotonic) toward the side with higher effective solute concentration (higher osmolarity; hypertonic), until the driving force is balanced.

Step-by-step solution

Step 1: Identify what can cross the membrane

Water can cross the membrane; sucrose cannot. Therefore, sucrose stays on its original side, and water is the component that redistributes.

Step 2: Convert molarity to osmolarity (effective solute concentration)

For a non-electrolyte like sucrose, the van’t Hoff factor is \(i \approx 1\), so:

\[ \text{osmolarity} = i \cdot M \]

Inside: \(i \cdot M = 1 \cdot 0.30 = 0.30\ \text{Osm}\)
Outside: \(i \cdot M = 1 \cdot 0.10 = 0.10\ \text{Osm}\)

Step 3: Assign tonicity (relative comparison)

The inside has the higher osmolarity (0.30 Osm). Therefore:

  • Inside is hypertonic relative to outside.
  • Outside is hypotonic relative to inside.

Step 4: Predict the direction of net water movement

Water moves from the hypotonic side (lower osmolarity) to the hypertonic side (higher osmolarity). Hence, net water movement is from outside to inside. In a physical simcell (for example, a dialysis tubing “cell”), the inside compartment typically gains water and increases in volume/mass.

Summary table

Compartment Solute Molarity (M) van’t Hoff factor \(i\) Osmolarity \(i \cdot M\) (Osm) Tonicity (relative)
Inside (simcell) Sucrose 0.30 1 0.30 Hypertonic (relative to outside)
Outside solution Sucrose 0.10 1 0.10 Hypotonic (relative to inside)

Visualization

Outside solution Inside (simcell) 0.10 M sucrose (0.10 Osm) 0.30 M sucrose (0.30 Osm) net H₂O movement hypotonic relative to inside hypertonic relative to outside
Two compartments are separated by a semipermeable (water-permeable) membrane. The right side has higher sucrose concentration, so it is hypertonic; net water movement is toward the right side.

Direct answers

  • Direction of net water movement: from the 0.10 M sucrose side (outside) to the 0.30 M sucrose side (inside).
  • Hypertonic side: the inside (0.30 M sucrose) is hypertonic relative to the outside.

Common checkpoints

  • Tonicity is relative: “hypertonic” must be stated relative to the other compartment.
  • Only nonpenetrating solutes matter: if sucrose could cross, tonicity would need to be re-evaluated; here sucrose is nonpenetrating by assumption.
  • Equilibrium idea: even when net flow becomes zero, water molecules still move both directions; the rates balance.
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